MOLECULAR MECHANISMS INVOLVED IN THE ANTICANCER ACTIVITY OF CROCIN AND CROCETIN, TWO BIOACTIVE COMPOUNDS FOUND IN SAFFRON

Molecular mechanisms involved in the anticancer activity of crocin and crocetin, two bioactive compounds found in saffron

Saffron, a valuable spice, possesses various medicinal properties including anticancer effects in addition to its aromatic qualities.Numerous studies have shown that bioactive compounds in saffron, especially crocin and crocetin, exhibit selective toxicity against cancer cells.This review aimed to comprehensively examine the anticancer mechanisms o

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Ras Downstream Effector GGCT Alleviates Oncogenic Stress

Summary: How cells adapt to oncogenic transformation-associated cellular stress and become fully transformed is still unknown.Here we identified a novel GGCT-regulated glutathione (GSH)-reactive oxygen species (ROS) metabolic pathway in oncogenic twizzlers pull and peel fruit punch stress alleviation.We identified GGCT as a target of oncogenic Ras

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